The 21c Museum Hotel in Louisville Kentucky is the first of its kind — a 90-room hotel dedicated to world class luxuries, Southern-style hospitality and contemporary art from living artists, exhibited throughout its galleries and public spaces.

Located in historic downtown Louisville, KY, the 21c hotel is within walking distance of downtown attractions, dining, and entertainment.

Guest rooms and suites at 21c are as unique as the art throughout the hotel complex. Accommodations are spacious and feature plush bedding, designer furniture, original art, the latest in technology and a few artistic surprises. Among the many upscale offerings: iPods with a wide variety of music for guests' listening pleasure, award winning design and décor, poster art, 42" HDTV flat screen televisions, WiFi, 500 thread count Egyptian cotton sheets imported from Italy crowning the exquisite bedding, silver mint julep cups, gourmet coffee makers, mini-bar refrigerators, Malin + Goetz bath amenities, and nightly turn down and Concierge services. Many guest rooms have exposed brick walls and offer views of the Ohio river, downtown or the indoor atrium.

The Proof on Main Restaurant, part of the 21c Hotel, features modern American food with Tuscan influences, showcasing the agricultural bounty of the Ohio River Valley. The place to be in the ‘Ville', Proof has been named one of America's 10 best new restaurants in 2006 by Esquire Magazine. Luscious libations, fantastic food, and superb service ensure your return to Proof on Main.

The hotel also offers a full exercise facility with a steam room, sauna and spa services. Relaxing spa rooms are available for massage therapy and spa treatments by appointment.

21c Museum is North America's first museum dedicated solely to collecting and exhibiting contemporary art of the 21st century. 21c Museum will host a series of dynamic group and solo exhibitions featuring emerging artists alongside acclaimed international artists.

21c Museum Hotel and Proof on Main Restaurant believe in the importance to "Always Strive to be Green." From the Windows to the floors, every effort has been made to restore and recycle materials during the construction and design of this luxurious Louisville hotel and restaurant. Come stay and find out what everyone is talking about.